All Research

Sub-part-per-trillion test of the Standard Model with atomic hydrogen

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Read the paperDOI: 10.1038/s41586-026-10124-3

TL;DR

Scientists made an incredibly precise measurement of light emitted by hydrogen atoms that tested one of physics' most fundamental theories - the Standard Model - to an accuracy of 0.7 parts per trillion. This measurement also resolved a long-standing disagreement about the size of protons by confirming the smaller value found in previous experiments with exotic atoms.

Quantum electrodynamics (QED), the first relativistic quantum field theory, describes light-matter interactions at a fundamental level and is one of the pillars of the Standard Model (SM). Through the extraordinary precision of QED, the SM predicts the energy levels of simple systems such as the hydrogen atom with up to 13 significant digits1, making hydrogen spectroscopy an ideal test bed. The consistency of physical constants extracted from different transitions in hydrogen using QED, such as the proton charge radius rp, constitutes a test of the theory. However, values of rp from recent measurements2-7 of atomic hydrogen are partly discrepant with each other and with a more precise value from spectroscopy of muonic hydrogen8,9. This prevents a test of QED at the level of experimental uncertainties. Here we present a measurement of the 2S-6P transition in atomic hydrogen with sufficient precision to distinguish between the discrepant values of rp and enable rigorous testing of QED and the SM overall. Our result ν2S-6P = 730,690,248,610.79(48) kHz gives a value of rp = 0.8406(15) fm at least 2.5-fold more precise than from other atomic hydrogen determinations and in excellent agreement with the muonic value. The SM prediction of the transition frequency (730,690,248,610.79(23) kHz) is in excellent agreement with our result, testing the SM to 0.7 parts per trillion (ppt) and, specifically, bound-state QED corrections to 0.5 parts per million (ppm), their most precise test so far.

  • 1Measured the 2S-6P transition frequency in hydrogen to be 730,690,248,610.79(48) kHz, achieving unprecedented precision
  • 2Determined the proton charge radius to be 0.8406(15) fm, which is 2.5 times more precise than previous atomic hydrogen measurements
  • 3Confirmed the smaller proton radius value from muonic hydrogen experiments, resolving the 'proton radius puzzle'
  • 4Tested the Standard Model to 0.7 parts per trillion accuracy - the most stringent test ever achieved
  • 5Validated quantum electrodynamics bound-state corrections to 0.5 parts per million precision
Nature Neuroscience·

Adversarial AI reveals mechanisms and treatments for disorders of consciousness

Imagine your brain is like a city with millions of roads and traffic systems. When you're awake and conscious, traffic flows in complex, coordinated patterns. In a coma, something has gone wrong — but we've never had a great way to figure out exactly which roads are broken or how to fix them. This study built a very smart AI that learned to tell the difference between 'awake brain' and 'coma brain' by studying hundreds of thousands of brainwave recordings. Then, like a detective, the AI was pitted against a simulated model of the brain to figure out: what changes in the brain's wiring would explain the difference? The AI figured out — on its own, without being told — that two key things go wrong in a coma: a specific circuit deep in the brain (called the basal ganglia indirect pathway) gets disrupted, and the brain's 'braking system' (inhibitory neurons) starts working too hard in the wrong places. The researchers then checked these predictions against real patient data, and both checked out. The AI also suggested that zapping a specific deep brain region with high-frequency electrical pulses might help wake people up — and early evidence from human patients supports this idea.

Disorders of consciousness
Artificial Intelligence
Nature·

Gene conversion empowers natural selection in a clonal fish species

Unfortunately, the content of this research abstract could not be accessed due to paywall restrictions. Without being able to read the actual findings about gene conversion in clonal fish species, I cannot provide an accurate explanation of what the researchers discovered or why it matters.

Science Advances·

Direct detection of an asteroid’s heliocentric deflection: The Didymos system after DART

NASA crashed a spacecraft into an asteroid moon called Dimorphos in 2022, and scientists have now measured that this impact actually nudged the entire asteroid system slightly off its path around the Sun. This is the first time humans have measurably changed how a celestial body orbits the Sun, proving that we can potentially deflect dangerous asteroids heading toward Earth.

Nature Astronomy·

The dynamics of AMPA receptors underlies the efficacy of ketamine in treatment resistant patients with depression

Think of your brain as having billions of tiny locks and keys. One particular lock — called the AMPA receptor — sits on brain cells and helps them talk to each other using the chemical glutamate. In people with hard-to-treat depression, this study found that those locks are less plentiful than normal, especially in emotional brain regions. When doctors gave these patients ketamine, it actually changed how many of those locks were available on the cell surface — and the bigger that change was, the better the patient felt. So ketamine isn't just temporarily numbing pain; it appears to be physically restoring a broken communication system in the brain. The scientists confirmed this by using a special brain scan (PET scan) with a radioactive tracer that literally glows where those AMPA receptor locks are located, letting them count them in real time in living people.

treatment-resistant depression
ketamine